BDBM50258904 CHEMBL4094525

SMILES: CCC(NC(=O)N1CC(=O)Nc2cccnc12)c1ccc(cc1)C1CC1

InChI Key: InChIKey=RTAWJAGHOPBLCR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50258904 (CHEMBL4094525) Show SMILES CCC(NC(=O)N1CC(=O)Nc2cccnc12)c1ccc(cc1)C1CC1 Show InChI InChI=1S/C20H22N4O2/c1-2-16(15-9-7-14(8-10-15)13-5-6-13)23-20(26)24-12-18(25)22-17-4-3-11-21-19(17)24/h3-4,7-11,13,16H,2,5-6,12H2,1H3,(H,22,25)(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assay				J Med Chem 60: 7677-7702 (2017) Article DOI: 10.1021/acs.jmedchem.7b00807 BindingDB Entry DOI: 10.7270/Q2P271JR
					More data for this Ligand-Target Pair