BDBM50258905 CHEMBL4084307

SMILES: CCC(NC(=O)N1CC(=O)Nc2cccnc12)c1ccc(cc1)N1CCC1

InChI Key: InChIKey=YIGNKHWIKRJNDY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258905   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50258905 (CHEMBL4084307) Show SMILES CCC(NC(=O)N1CC(=O)Nc2cccnc12)c1ccc(cc1)N1CCC1 Show InChI InChI=1S/C20H23N5O2/c1-2-16(14-6-8-15(9-7-14)24-11-4-12-24)23-20(27)25-13-18(26)22-17-5-3-10-21-19(17)25/h3,5-10,16H,2,4,11-13H2,1H3,(H,22,26)(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of recombinant human FLAG-tagged PDE2A3 expressed in sf21 cells using [3H]cGMP as substrate by scintillation proximity assay				J Med Chem 60: 7677-7702 (2017) Article DOI: 10.1021/acs.jmedchem.7b00807 BindingDB Entry DOI: 10.7270/Q2P271JR
					More data for this Ligand-Target Pair