BDBM50259028 CHEMBL4091339

SMILES: O=C(Oc1ccc2C(=O)c3nc4nonc4nc3-c2c1)c1ccccc1

InChI Key: InChIKey=OXVQYEBFDQUEEC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50259028 (CHEMBL4091339) Show SMILES O=C(Oc1ccc2C(=O)c3nc4nonc4nc3-c2c1)c1ccccc1 Show InChI InChI=1S/C18H8N4O4/c23-15-11-7-6-10(25-18(24)9-4-2-1-3-5-9)8-12(11)13-14(15)20-17-16(19-13)21-26-22-17/h1-8H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Salerno Curated by ChEMBL					Assay Description Inhibition of mPGES-1 in microsomes isolated from IL-1beta-stimulated human A549 cells using PGH2 as substrate preincubated for 15 mins followed by s...				Eur J Med Chem 125: 278-287 (2017) Article DOI: 10.1016/j.ejmech.2016.09.042 BindingDB Entry DOI: 10.7270/Q2WM1GV8
					More data for this Ligand-Target Pair