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SMILES: FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=JBFQRHXWMOVCLP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259542   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 2 subunit alpha


(Homo sapiens (Human))		BDBM50259542
PNG
(2-(3-Trifluoromethylphenyl)-4(5)-(3-trifluoromethy...)
Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H10F6N2/c18-16(19,20)12-5-1-3-10(7-12)14-9-24-15(25-14)11-4-2-6-13(8-11)17(21,22)23/h1-9H,(H,24,25)
PDB

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Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Università degli Studi di Parma

Curated by ChEMBL


Assay Description
Inhibition of human Nav1.2 channel expressed in HEK cells by patch-clamp electrophysiology method

Bioorg Med Chem 17: 3642-8 (2009)


Article DOI: 10.1016/j.bmc.2009.03.067
BindingDB Entry DOI: 10.7270/Q2GQ6XN5
More data for this
Ligand-Target Pair