BDBM50259870 CHEMBL481437::psammaplysene A

SMILES: CN(C)CCCOc1c(Br)cc(\C=C\C(=O)NCCCOc2c(Br)cc(CCN(C)C)cc2Br)cc1Br

InChI Key: InChIKey=PKWUEPCKAUUBLY-BQYQJAHWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Forkhead box protein O1 (Homo sapiens (Human))	BDBM50259870 (CHEMBL481437 | psammaplysene A) Show SMILES CN(C)CCCOc1c(Br)cc(\C=C\C(=O)NCCCOc2c(Br)cc(CCN(C)C)cc2Br)cc1Br Show InChI InChI=1S/C27H35Br4N3O3/c1-33(2)11-6-14-37-27-21(28)15-19(16-22(27)29)7-8-25(35)32-10-5-13-36-26-23(30)17-20(18-24(26)31)9-12-34(3)4/h7-8,15-18H,5-6,9-14H2,1-4H3,(H,32,35)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of FOXO1a (unknown origin) nuclear export in PTEN-deficient cells				J Nat Prod 68: 574-6 (2005) Article DOI: 10.1021/np049624z BindingDB Entry DOI: 10.7270/Q2CR5T47
					More data for this Ligand-Target Pair