BDBM50260034 CHEMBL4077200

SMILES: CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(C)(C)C)c1cncnc1

InChI Key: InChIKey=NVSACWLSRUGEMJ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50260034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50260034 (CHEMBL4077200) Show SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(C)(C)C)c1cncnc1 Show InChI InChI=1S/C31H40N6O/c1-22-18-37(28-16-32-21-33-17-28)20-25-14-24(6-7-29(22)25)30(38)34-27-13-23(12-26(15-27)31(2,3)4)19-36-10-8-35(5)9-11-36/h6-7,12-17,21-22H,8-11,18-20H2,1-5H3,(H,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged DDR2 cytoplasmic domain expressed in baculovirus expression system using Fluorescein-Poly GAT as substrate...				ACS Med Chem Lett 8: 327-332 (2017) Article DOI: 10.1021/acsmedchemlett.6b00497 BindingDB Entry DOI: 10.7270/Q2N0190M
					More data for this Ligand-Target Pair
Bcr-Abl (Homo sapiens (Human))	BDBM50260034 (CHEMBL4077200) Show SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(C)(C)C)c1cncnc1 Show InChI InChI=1S/C31H40N6O/c1-22-18-37(28-16-32-21-33-17-28)20-25-14-24(6-7-29(22)25)30(38)34-27-13-23(12-26(15-27)31(2,3)4)19-36-10-8-35(5)9-11-36/h6-7,12-17,21-22H,8-11,18-20H2,1-5H3,(H,34,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of recombinant human full length His-tagged Bcr-Abl fusion protein cytoplasmic domain expressed in baculovirus expression system using tyr...				ACS Med Chem Lett 8: 327-332 (2017) Article DOI: 10.1021/acsmedchemlett.6b00497 BindingDB Entry DOI: 10.7270/Q2N0190M
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50260034 (CHEMBL4077200) Show SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(C)(C)C)c1cncnc1 Show InChI InChI=1S/C31H40N6O/c1-22-18-37(28-16-32-21-33-17-28)20-25-14-24(6-7-29(22)25)30(38)34-27-13-23(12-26(15-27)31(2,3)4)19-36-10-8-35(5)9-11-36/h6-7,12-17,21-22H,8-11,18-20H2,1-5H3,(H,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged c-kit cytoplasmic domain (544 to 976 residues) expressed in baculovirus expression system using Ser/Thr 6 ...				ACS Med Chem Lett 8: 327-332 (2017) Article DOI: 10.1021/acsmedchemlett.6b00497 BindingDB Entry DOI: 10.7270/Q2N0190M
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human))	BDBM50260034 (CHEMBL4077200) Show SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(C)(C)C)c1cncnc1 Show InChI InChI=1S/C31H40N6O/c1-22-18-37(28-16-32-21-33-17-28)20-25-14-24(6-7-29(22)25)30(38)34-27-13-23(12-26(15-27)31(2,3)4)19-36-10-8-35(5)9-11-36/h6-7,12-17,21-22H,8-11,18-20H2,1-5H3,(H,34,38)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged DDR1 catalytic domain expressed in baculovirus expression system using Fluorescein-Poly GAT as substrate m...				ACS Med Chem Lett 8: 327-332 (2017) Article DOI: 10.1021/acsmedchemlett.6b00497 BindingDB Entry DOI: 10.7270/Q2N0190M
					More data for this Ligand-Target Pair