null

SMILES: [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)Oc1cc(OCCCCOc2cc(OS([O-])(=O)=O)cc3oc(-c4ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c4)c(OS([O-])(=O)=O)c(=O)c23)c2c(c1)oc(-c1ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c1)c(OS([O-])(=O)=O)c2=O

InChI Key: InChIKey=ITRZYFUIRDSZSS-UHFFFAOYSA-F

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50260058 (CHEMBL4095129) Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)Oc1cc(OCCCCOc2cc(OS([O-])(=O)=O)cc3oc(-c4ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c4)c(OS([O-])(=O)=O)c(=O)c23)c2c(c1)oc(-c1ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c1)c(OS([O-])(=O)=O)c2=O Show InChI InChI=1S/C34H26O38S8/c35-29-27-23(11-17(65-73(37,38)39)13-25(27)63-31(33(29)71-79(55,56)57)15-3-5-19(67-75(43,44)45)21(9-15)69-77(49,50)51)61-7-1-2-8-62-24-12-18(66-74(40,41)42)14-26-28(24)30(36)34(72-80(58,59)60)32(64-26)16-4-6-20(68-76(46,47)48)22(10-16)70-78(52,53)54/h3-6,9-14H,1-2,7-8H2,(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)/p-8	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase using S1384 as substrate preincubated for 5 mins followed by substrate addition				J Med Chem 62: 5501-5511 (2019) Article DOI: 10.1021/acs.jmedchem.9b00379
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50260058 (CHEMBL4095129) Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)Oc1cc(OCCCCOc2cc(OS([O-])(=O)=O)cc3oc(-c4ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c4)c(OS([O-])(=O)=O)c(=O)c23)c2c(c1)oc(-c1ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c1)c(OS([O-])(=O)=O)c2=O Show InChI InChI=1S/C34H26O38S8/c35-29-27-23(11-17(65-73(37,38)39)13-25(27)63-31(33(29)71-79(55,56)57)15-3-5-19(67-75(43,44)45)21(9-15)69-77(49,50)51)61-7-1-2-8-62-24-12-18(66-74(40,41)42)14-26-28(24)30(36)34(72-80(58,59)60)32(64-26)16-4-6-20(68-76(46,47)48)22(10-16)70-78(52,53)54/h3-6,9-14H,1-2,7-8H2,(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)/p-8	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Medicinal Chemistry, and Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University , Richmond, Virginia 23219, United States. Curated by ChEMBL					Assay Description Allosteric inhibition of full length human plasmin by using chromogenic substrate spectrozyme PL preincubated for 5 mins followed by substrate additi...				J Med Chem 60: 641-657 (2017) Article DOI: 10.1021/acs.jmedchem.6b01474 BindingDB Entry DOI: 10.7270/Q2CF9SJM
					More data for this Ligand-Target Pair