BDBM50260340 9-Benzyloxy-1H-pyrido[3'4':4,5]pyrrolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dione::CHEMBL523179

SMILES: O=C1NC(=O)c2c1c1c3cnccc3[nH]c1c1[nH]c3ccc(OCc4ccccc4)cc3c21

InChI Key: InChIKey=PJHIDXBBDKQFEC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50260340 (9-Benzyloxy-1H-pyrido[3'4':4,5]pyrrolo[2,3-a]pyrro...) Show SMILES O=C1NC(=O)c2c1c1c3cnccc3[nH]c1c1[nH]c3ccc(OCc4ccccc4)cc3c21 Show InChI InChI=1S/C26H16N4O3/c31-25-21-19-15-10-14(33-12-13-4-2-1-3-5-13)6-7-17(15)28-23(19)24-20(22(21)26(32)30-25)16-11-27-9-8-18(16)29-24/h1-11,28-29H,12H2,(H,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Inhibition of human Chk1 expressed in sf9-baculovirus system				Bioorg Med Chem 16: 5303-21 (2008) Article DOI: 10.1016/j.bmc.2008.02.086 BindingDB Entry DOI: 10.7270/Q2V124KR
					More data for this Ligand-Target Pair