BDBM50260545 CHEMBL4090634

SMILES: N[C@H](COc1cncc(n1)-c1ccc2c(c[nH]c2c1)-c1ccc(N)nc1F)c1ccccc1

InChI Key: InChIKey=XMYBFHQGQPKHNT-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50260545 (CHEMBL4090634) Show SMILES N[C@H](COc1cncc(n1)-c1ccc2c(c[nH]c2c1)-c1ccc(N)nc1F)c1ccccc1 |r| Show InChI InChI=1S/C25H21FN6O/c26-25-18(8-9-23(28)32-25)19-11-30-21-10-16(6-7-17(19)21)22-12-29-13-24(31-22)33-14-20(27)15-4-2-1-3-5-15/h1-13,20,30H,14,27H2,(H2,28,32)/t20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Zarqa University Curated by ChEMBL					Assay Description Inhibition of human recombinant PIM1 in presence of ATP by ELISA based spectrophotometric analysis				Bioorg Med Chem 25: 4855-4875 (2017) Article DOI: 10.1016/j.bmc.2017.07.036 BindingDB Entry DOI: 10.7270/Q2BC420V
					More data for this Ligand-Target Pair