null
SMILES: Cc1nc2C(Cl)CCCn2c(=O)c1CCN1CCN(CC1)c1nsc2ccccc12
InChI Key: InChIKey=PEIASVYGZCGDSL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50260616 (CHEMBL4101115) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinjiang Technical Institute of Physics and Chemistry Curated by ChEMBL | Assay Description Antagonist activity at 5-HT2A receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assay | Bioorg Med Chem 25: 4904-4916 (2017) Article DOI: 10.1016/j.bmc.2017.07.040 BindingDB Entry DOI: 10.7270/Q2Z3222T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50260616 (CHEMBL4101115) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Xinjiang Technical Institute of Physics and Chemistry Curated by ChEMBL | Assay Description Antagonist activity at dopamine D2 receptor (unknown origin) after 60 mins by Ultra lance cAMP assay | Bioorg Med Chem 25: 4904-4916 (2017) Article DOI: 10.1016/j.bmc.2017.07.040 BindingDB Entry DOI: 10.7270/Q2Z3222T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50260616 (CHEMBL4101115) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 488 | n/a | n/a | n/a | n/a |
Xinjiang Technical Institute of Physics and Chemistry Curated by ChEMBL | Assay Description Agonist activity at 5-HT1A receptor (unknown origin) after 60 mins by Ultra lance cAMP assay | Bioorg Med Chem 25: 4904-4916 (2017) Article DOI: 10.1016/j.bmc.2017.07.040 BindingDB Entry DOI: 10.7270/Q2Z3222T | |||||||||||
More data for this Ligand-Target Pair |