BDBM50260632 2-((1S,4S)-5-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imidazol-5-yl)-2,5-diaza-bicyclo[2.2.1]heptan-2-yl)ethanol::CHEMBL523724

SMILES: CCC(CC)Sc1nc2cc(Cl)c(cc2[nH]1)N1C[C@@H]2C[C@H]1CN2CCO

InChI Key: InChIKey=INBDCFQVZRNXGZ-STQMWFEESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50260632 (2-((1S,4S)-5-(6-chloro-2-(pentan-3-ylthio)-3H-benz...) Show SMILES CCC(CC)Sc1nc2cc(Cl)c(cc2[nH]1)N1C[C@@H]2C[C@H]1CN2CCO |r| Show InChI InChI=1S/C19H27ClN4OS/c1-3-14(4-2)26-19-21-16-8-15(20)18(9-17(16)22-19)24-11-12-7-13(24)10-23(12)5-6-25/h8-9,12-14,25H,3-7,10-11H2,1-2H3,(H,21,22)/t12-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 18: 3282-5 (2008) Article DOI: 10.1016/j.bmcl.2008.04.037 BindingDB Entry DOI: 10.7270/Q2542NDJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50260632 (2-((1S,4S)-5-(6-chloro-2-(pentan-3-ylthio)-3H-benz...) Show SMILES CCC(CC)Sc1nc2cc(Cl)c(cc2[nH]1)N1C[C@@H]2C[C@H]1CN2CCO |r| Show InChI InChI=1S/C19H27ClN4OS/c1-3-14(4-2)26-19-21-16-8-15(20)18(9-17(16)22-19)24-11-12-7-13(24)10-23(12)5-6-25/h8-9,12-14,25H,3-7,10-11H2,1-2H3,(H,21,22)/t12-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptor				Bioorg Med Chem Lett 18: 3282-5 (2008) Article DOI: 10.1016/j.bmcl.2008.04.037 BindingDB Entry DOI: 10.7270/Q2542NDJ
					More data for this Ligand-Target Pair