BDBM50260664 (S)-2-Benzenesulfonyl-6,10-dioxa-2-aza-spiro[4.5]-decane-3-carboxylic acid hydroxyamide::CHEMBL494976

SMILES: ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCO2

InChI Key: InChIKey=BMWSCLBVMGXTRY-LBPRGKRZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260664   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50260664 ((S)-2-Benzenesulfonyl-6,10-dioxa-2-aza-spiro[4.5]-...) Show SMILES ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCO2 |r| Show InChI InChI=1S/C14H18N2O6S/c17-13(15-18)12-9-14(21-7-4-8-22-14)10-16(12)23(19,20)11-5-2-1-3-6-11/h1-3,5-6,12,18H,4,7-10H2,(H,15,17)/t12-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of aminopeptidase N (unknown origin)				Bioorg Med Chem 16: 5398-404 (2008) Article DOI: 10.1016/j.bmc.2008.04.027 BindingDB Entry DOI: 10.7270/Q22B8XTN
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50260664 ((S)-2-Benzenesulfonyl-6,10-dioxa-2-aza-spiro[4.5]-...) Show SMILES ONC(=O)[C@@H]1CC2(CN1S(=O)(=O)c1ccccc1)OCCCO2 |r| Show InChI InChI=1S/C14H18N2O6S/c17-13(15-18)12-9-14(21-7-4-8-22-14)10-16(12)23(19,20)11-5-2-1-3-6-11/h1-3,5-6,12,18H,4,7-10H2,(H,15,17)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of MMP2 (unknown origin)				Bioorg Med Chem 16: 5398-404 (2008) Article DOI: 10.1016/j.bmc.2008.04.027 BindingDB Entry DOI: 10.7270/Q22B8XTN
					More data for this Ligand-Target Pair