Found 4 hits for monomerid = 50260666 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50260666
(3-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)Show InChI InChI=1S/C19H18ClN3O/c1-23-17(13-4-2-5-16(24)12-13)21-22-18(23)19(10-3-11-19)14-6-8-15(20)9-7-14/h2,4-9,12,24H,3,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human 11beta HSD1 by SPA assay |
Bioorg Med Chem Lett 18: 3405-11 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.013 BindingDB Entry DOI: 10.7270/Q2XP74QM |
More data for this Ligand-Target Pair | |
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2)
(Mus musculus (mouse)) | BDBM50260666
(3-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)Show InChI InChI=1S/C19H18ClN3O/c1-23-17(13-4-2-5-16(24)12-13)21-22-18(23)19(10-3-11-19)14-6-8-15(20)9-7-14/h2,4-9,12,24H,3,10-11H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of mouse 11beta HSD2 |
Bioorg Med Chem Lett 18: 3405-11 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.013 BindingDB Entry DOI: 10.7270/Q2XP74QM |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 2
(Homo sapiens (Human)) | BDBM50260666
(3-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)Show InChI InChI=1S/C19H18ClN3O/c1-23-17(13-4-2-5-16(24)12-13)21-22-18(23)19(10-3-11-19)14-6-8-15(20)9-7-14/h2,4-9,12,24H,3,10-11H2,1H3 | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human 11beta HSD2 |
Bioorg Med Chem Lett 18: 3405-11 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.013 BindingDB Entry DOI: 10.7270/Q2XP74QM |
More data for this Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 1
(Mus musculus (mouse)) | BDBM50260666
(3-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)Show InChI InChI=1S/C19H18ClN3O/c1-23-17(13-4-2-5-16(24)12-13)21-22-18(23)19(10-3-11-19)14-6-8-15(20)9-7-14/h2,4-9,12,24H,3,10-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of mouse 11beta HSD1 by SPA assay |
Bioorg Med Chem Lett 18: 3405-11 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.013 BindingDB Entry DOI: 10.7270/Q2XP74QM |
More data for this Ligand-Target Pair | |