BDBM50261174 CHEMBL496930::corymbone B

SMILES: CC(C)CC(C1C(=O)C(C)(C)C(=O)C(C)(C)C1=O)c1c(O)c(C)c(O)c(C(=O)CCc2ccccc2)c1O

InChI Key: InChIKey=HNWCPMSYUQJXMZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyrotropin-releasing hormone receptor 2 (Rattus norvegicus)	BDBM50261174 (CHEMBL496930 | corymbone B) Show SMILES CC(C)CC(C1C(=O)C(C)(C)C(=O)C(C)(C)C1=O)c1c(O)c(C)c(O)c(C(=O)CCc2ccccc2)c1O Show InChI InChI=1S/C31H38O7/c1-16(2)15-19(22-27(36)30(4,5)29(38)31(6,7)28(22)37)21-24(33)17(3)25(34)23(26(21)35)20(32)14-13-18-11-9-8-10-12-18/h8-12,16,19,22,33-35H,13-15H2,1-7H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Griffith University Curated by ChEMBL					Assay Description Displacement of [3H]3-methylhistidyl-TRH from rat recombinant TRH2 receptor expressed in HEK2935 cells				J Nat Prod 71: 881-3 (2008) Article DOI: 10.1021/np0706567 BindingDB Entry DOI: 10.7270/Q2ZK5GFP
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