| Reaction Details |
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 | Report a problem with these data |
| Target | Thyrotropin-releasing hormone receptor |
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| Ligand | BDBM50261174 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_533265 (CHEMBL973283) |
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| IC50 | 19000±n/a nM |
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| Citation |  Carroll, AR; Urban, S; Lamb, J; Moni, R; Guymer, GP; Forster, PI; Quinn, RJ Corymbones A and B, phloroglucinols with thyrotropin releasing hormone receptor 2 binding affinity from the flowers of Corymbia peltata. J Nat Prod71:881-3 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thyrotropin-releasing hormone receptor |
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| Name: | Thyrotropin-releasing hormone receptor |
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| Synonyms: | Thyrotropin-releasing hormone receptor 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39044.21 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_532304 |
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| Residue: | 352 |
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| Sequence: | MDGPSNVSLIHGDTTLGLPEYKVVSVFLVLLVCTLGIVGNAMVILVVLTSRDMHTPTNCY
LVSLALADLLVLLAAGLPNVSDSLVGHWIYGRAGCLGITYFQYLGINVSSFSILAFTVER
YIAICHPLRAQTVCTVARAKRIIAGIWGVTSLYCLLWFFLVDLNVRDNQRLECGYKVPRG
LYLPIYLLDFAVFFIGPLLVTLVLYGLIGRILFQSPLSQEAWQKERQPHGQSEAAPGNCS
RAKSSRKQATRMLAVVVLLFAVLWTPYRTLVLLNSFVAQPFLDPWVLLFCRTCVYTNSAV
NPVVYSLMSQKFRAAFLKLCWCRAAGPQRRAARVLTSNYSAAQETSEGTEKM
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| BDBM50261174 |
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| n/a |
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| Name | BDBM50261174 |
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| Synonyms: | CHEMBL496930 | corymbone B |
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| Type | Small organic molecule |
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| Emp. Form. | C31H38O7 |
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| Mol. Mass. | 522.6292 |
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| SMILES | CC(C)CC(C1C(=O)C(C)(C)C(=O)C(C)(C)C1=O)c1c(O)c(C)c(O)c(C(=O)CCc2ccccc2)c1O |
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| Structure | 
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