BDBM50261264 1-(2-(6-(2-Acetamidobenzo[d]thiazol-4-yloxy)pyrimidin-4-yl)-5-(trifluoromethyl)phenyl)-3-tert-butylurea::CHEMBL467600

SMILES: CC(=O)Nc1nc2c(Oc3cc(ncn3)-c3ccc(cc3NC(=O)NC(C)(C)C)C(F)(F)F)cccc2s1

InChI Key: InChIKey=DFWCPUUEAHOEHM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50261264 (1-(2-(6-(2-Acetamidobenzo[d]thiazol-4-yloxy)pyrimi...) Show SMILES CC(=O)Nc1nc2c(Oc3cc(ncn3)-c3ccc(cc3NC(=O)NC(C)(C)C)C(F)(F)F)cccc2s1 Show InChI InChI=1S/C25H23F3N6O3S/c1-13(35)31-23-33-21-18(6-5-7-19(21)38-23)37-20-11-16(29-12-30-20)15-9-8-14(25(26,27)28)10-17(15)32-22(36)34-24(2,3)4/h5-12H,1-4H3,(H,31,33,35)(H2,32,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx				J Med Chem 51: 2744-57 (2008) Article DOI: 10.1021/jm7014638 BindingDB Entry DOI: 10.7270/Q2930SZH
					More data for this Ligand-Target Pair
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50261264 (1-(2-(6-(2-Acetamidobenzo[d]thiazol-4-yloxy)pyrimi...) Show SMILES CC(=O)Nc1nc2c(Oc3cc(ncn3)-c3ccc(cc3NC(=O)NC(C)(C)C)C(F)(F)F)cccc2s1 Show InChI InChI=1S/C25H23F3N6O3S/c1-13(35)31-23-33-21-18(6-5-7-19(21)38-23)37-20-11-16(29-12-30-20)15-9-8-14(25(26,27)28)10-17(15)32-22(36)34-24(2,3)4/h5-12H,1-4H3,(H,31,33,35)(H2,32,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx				J Med Chem 51: 2744-57 (2008) Article DOI: 10.1021/jm7014638 BindingDB Entry DOI: 10.7270/Q2930SZH
					More data for this Ligand-Target Pair