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BDBM50261496 CHEMBL4097272

SMILES: COc1ccc2n(c(C)c(CC(=O)NS(=O)(=O)c3ccccc3)c2c1)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=FBCSLIIJAKJPMP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261496   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50261496
PNG
(CHEMBL4097272)
Show SMILES COc1ccc2n(c(C)c(CC(=O)NS(=O)(=O)c3ccccc3)c2c1)-c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C30H26N2O4S/c1-21-27(20-30(33)31-37(34,35)26-11-7-4-8-12-26)28-19-25(36-2)17-18-29(28)32(21)24-15-13-23(14-16-24)22-9-5-3-6-10-22/h3-19H,20H2,1-2H3,(H,31,33)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
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AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of 5-FAM-Bid-BH3 peptide binding to Bcl2 (unknown origin) pre-incubated for 30 mins followed by further incubation with 5-FAM-Bid-BH3 pept...

Bioorg Med Chem 25: 5548-5556 (2017)


Article DOI: 10.1016/j.bmc.2017.08.024
BindingDB Entry DOI: 10.7270/Q2FX7CX8
More data for this
Ligand-Target Pair