BindingDB logo
myBDB logout

BDBM50261664 CHEMBL4067601

SMILES: C[C@@H](N[C@H]1CCN(C1)c1ccc(cc1)S(=O)(=O)NCCN(C)C)c1cccc2ccccc12

InChI Key: InChIKey=NIBNVKBNBRPMHY-IRLDBZIGSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261664   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))		BDBM50261664
PNG
(CHEMBL4067601)
Show SMILES C[C@@H](N[C@H]1CCN(C1)c1ccc(cc1)S(=O)(=O)NCCN(C)C)c1cccc2ccccc12 |r|
Show InChI InChI=1S/C26H34N4O2S/c1-20(25-10-6-8-21-7-4-5-9-26(21)25)28-22-15-17-30(19-22)23-11-13-24(14-12-23)33(31,32)27-16-18-29(2)3/h4-14,20,22,27-28H,15-19H2,1-3H3/t20-,22+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Enteroendocrine Discovery Performance Unit and Platform Technologies and Science, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709, United States. Electronic address: ssparks@viamet.c

Curated by ChEMBL


Assay Description
Agonist activity at human beta-2 adrenergic receptor expressed in human H292 cells assessed as accumulation of intracellular cAMP after 1 hr by Alpha...

Bioorg Med Chem Lett 27: 4673-4677 (2017)


Article DOI: 10.1016/j.bmcl.2017.09.008
BindingDB Entry DOI: 10.7270/Q29889FR
More data for this
Ligand-Target Pair