BDBM50261691 CHEMBL4094738

SMILES: C[C@@H](N[C@H]1CCN(C1)c1ccc(cc1)S(=O)(=O)NCC(O)=O)c1cccc2ccccc12

InChI Key: InChIKey=BDQQUJJPVUSJGA-MJGOQNOKSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50261691 (CHEMBL4094738) Show SMILES C[C@@H](N[C@H]1CCN(C1)c1ccc(cc1)S(=O)(=O)NCC(O)=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C24H27N3O4S/c1-17(22-8-4-6-18-5-2-3-7-23(18)22)26-19-13-14-27(16-19)20-9-11-21(12-10-20)32(30,31)25-15-24(28)29/h2-12,17,19,25-26H,13-16H2,1H3,(H,28,29)/t17-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Enteroendocrine Discovery Performance Unit and Platform Technologies and Science, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709, United States. Electronic address: ssparks@viamet.c Curated by ChEMBL					Assay Description Displacement of [3H]-Ro- 15-4513 from alpha6 beta2 gamma2 subunits of Rat GABA-A receptor expressed in Sf-9 insect cell membranes				Bioorg Med Chem Lett 27: 4673-4677 (2017) Article DOI: 10.1016/j.bmcl.2017.09.008 BindingDB Entry DOI: 10.7270/Q29889FR
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