BDBM50261695 CHEMBL4092377

SMILES: C[C@@H](N[C@H]1CCN(C1)c1ccc(cc1)C(=O)NCCS(O)(=O)=O)c1cccc2ccccc12

InChI Key: InChIKey=ATKRVTITMZGBBL-NQIIRXRSSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50261695 (CHEMBL4092377) Show SMILES C[C@@H](N[C@H]1CCN(C1)c1ccc(cc1)C(=O)NCCS(O)(=O)=O)c1cccc2ccccc12 |r| Show InChI InChI=1S/C25H29N3O4S/c1-18(23-8-4-6-19-5-2-3-7-24(19)23)27-21-13-15-28(17-21)22-11-9-20(10-12-22)25(29)26-14-16-33(30,31)32/h2-12,18,21,27H,13-17H2,1H3,(H,26,29)(H,30,31,32)/t18-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Enteroendocrine Discovery Performance Unit and Platform Technologies and Science, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709, United States. Electronic address: ssparks@viamet.c Curated by ChEMBL					Assay Description Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assay				Bioorg Med Chem Lett 27: 4673-4677 (2017) Article DOI: 10.1016/j.bmcl.2017.09.008 BindingDB Entry DOI: 10.7270/Q29889FR
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