BDBM50261751 CHEMBL469274::tert-butyl 3-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenylcarbamate

SMILES: CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCCCC(=O)NO

InChI Key: InChIKey=TVNHLWWJVGGFQS-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50261751 (CHEMBL469274 | tert-butyl 3-(3-((7-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C22H30N4O6/c1-22(2,3)31-21(29)24-16-10-8-9-15(13-16)18-14-17(26-32-18)20(28)23-12-7-5-4-6-11-19(27)25-30/h8-10,13-14,30H,4-7,11-12H2,1-3H3,(H,23,28)(H,24,29)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair
Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50261751 (CHEMBL469274 | tert-butyl 3-(3-((7-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C22H30N4O6/c1-22(2,3)31-21(29)24-16-10-8-9-15(13-16)18-14-17(26-32-18)20(28)23-12-7-5-4-6-11-19(27)25-30/h8-10,13-14,30H,4-7,11-12H2,1-3H3,(H,23,28)(H,24,29)(H,25,27)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28.2	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC10 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50261751 (CHEMBL469274 | tert-butyl 3-(3-((7-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C22H30N4O6/c1-22(2,3)31-21(29)24-16-10-8-9-15(13-16)18-14-17(26-32-18)20(28)23-12-7-5-4-6-11-19(27)25-30/h8-10,13-14,30H,4-7,11-12H2,1-3H3,(H,23,28)(H,24,29)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50261751 (CHEMBL469274 | tert-butyl 3-(3-((7-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCCCC(=O)NO Show InChI InChI=1S/C22H30N4O6/c1-22(2,3)31-21(29)24-16-10-8-9-15(13-16)18-14-17(26-32-18)20(28)23-12-7-5-4-6-11-19(27)25-30/h8-10,13-14,30H,4-7,11-12H2,1-3H3,(H,23,28)(H,24,29)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair