BDBM50261752 CHEMBL469275::tert-butyl 3-(3-((5-(hydroxyamino)-5-oxopentyl)carbamoyl)isoxazol-5-yl)phenylcarbamate

SMILES: CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCC(=O)NO

InChI Key: InChIKey=HPDGNTVEPAKSPV-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50261752   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50261752 (CHEMBL469275 | tert-butyl 3-(3-((5-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCC(=O)NO Show InChI InChI=1S/C20H26N4O6/c1-20(2,3)29-19(27)22-14-8-6-7-13(11-14)16-12-15(24-30-16)18(26)21-10-5-4-9-17(25)23-28/h6-8,11-12,28H,4-5,9-10H2,1-3H3,(H,21,26)(H,22,27)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	826	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50261752 (CHEMBL469275 | tert-butyl 3-(3-((5-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCC(=O)NO Show InChI InChI=1S/C20H26N4O6/c1-20(2,3)29-19(27)22-14-8-6-7-13(11-14)16-12-15(24-30-16)18(26)21-10-5-4-9-17(25)23-28/h6-8,11-12,28H,4-5,9-10H2,1-3H3,(H,21,26)(H,22,27)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC2 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair
Histone deacetylase 10 (Homo sapiens (Human))	BDBM50261752 (CHEMBL469275 | tert-butyl 3-(3-((5-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCC(=O)NO Show InChI InChI=1S/C20H26N4O6/c1-20(2,3)29-19(27)22-14-8-6-7-13(11-14)16-12-15(24-30-16)18(26)21-10-5-4-9-17(25)23-28/h6-8,11-12,28H,4-5,9-10H2,1-3H3,(H,21,26)(H,22,27)(H,23,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	891	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC10 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50261752 (CHEMBL469275 | tert-butyl 3-(3-((5-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCC(=O)NO Show InChI InChI=1S/C20H26N4O6/c1-20(2,3)29-19(27)22-14-8-6-7-13(11-14)16-12-15(24-30-16)18(26)21-10-5-4-9-17(25)23-28/h6-8,11-12,28H,4-5,9-10H2,1-3H3,(H,21,26)(H,22,27)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50261752 (CHEMBL469275 | tert-butyl 3-(3-((5-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCC(=O)NO Show InChI InChI=1S/C20H26N4O6/c1-20(2,3)29-19(27)22-14-8-6-7-13(11-14)16-12-15(24-30-16)18(26)21-10-5-4-9-17(25)23-28/h6-8,11-12,28H,4-5,9-10H2,1-3H3,(H,21,26)(H,22,27)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50261752 (CHEMBL469275 | tert-butyl 3-(3-((5-(hydroxyamino)-...) Show SMILES CC(C)(C)OC(=O)Nc1cccc(c1)-c1cc(no1)C(=O)NCCCCC(=O)NO Show InChI InChI=1S/C20H26N4O6/c1-20(2,3)29-19(27)22-14-8-6-7-13(11-14)16-12-15(24-30-16)18(26)21-10-5-4-9-17(25)23-28/h6-8,11-12,28H,4-5,9-10H2,1-3H3,(H,21,26)(H,22,27)(H,23,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83.6	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of HDAC3 (unknown origin) after 17 hrs				J Med Chem 51: 4370-3 (2008) Article DOI: 10.1021/jm8002894 BindingDB Entry DOI: 10.7270/Q27W6C11
					More data for this Ligand-Target Pair