null

SMILES: CCN(CC)CCn1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O

InChI Key: InChIKey=GHHXRRBAWPYQTC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50261853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50261853 (CHEMBL4102030) Show SMILES CCN(CC)CCn1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O Show InChI InChI=1S/C14H17Cl2IN4O/c1-3-20(4-2)5-6-21-12(17)11(16)10-8(15)7-9(13(18)22)19-14(10)21/h7H,3-6H2,1-2H3,(H2,18,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
IDD Medicinal Chemistry, Sanofi Genzyme, 153 Second Avenue, Waltham, MA 02451, USA. Electronic address: claude.barberis2@sanofi.com. Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assay				Bioorg Med Chem Lett 27: 4735-4740 (2017) Article DOI: 10.1016/j.bmcl.2017.08.068 BindingDB Entry DOI: 10.7270/Q2NG4T34
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50261853 (CHEMBL4102030) Show SMILES CCN(CC)CCn1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O Show InChI InChI=1S/C14H17Cl2IN4O/c1-3-20(4-2)5-6-21-12(17)11(16)10-8(15)7-9(13(18)22)19-14(10)21/h7H,3-6H2,1-2H3,(H2,18,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
IDD Medicinal Chemistry, Sanofi Genzyme, 153 Second Avenue, Waltham, MA 02451, USA. Electronic address: claude.barberis2@sanofi.com. Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis H37RV InhA				Bioorg Med Chem Lett 27: 4735-4740 (2017) Article DOI: 10.1016/j.bmcl.2017.08.068 BindingDB Entry DOI: 10.7270/Q2NG4T34
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50261853 (CHEMBL4102030) Show SMILES CCN(CC)CCn1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O Show InChI InChI=1S/C14H17Cl2IN4O/c1-3-20(4-2)5-6-21-12(17)11(16)10-8(15)7-9(13(18)22)19-14(10)21/h7H,3-6H2,1-2H3,(H2,18,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
IDD Medicinal Chemistry, Sanofi Genzyme, 153 Second Avenue, Waltham, MA 02451, USA. Electronic address: claude.barberis2@sanofi.com. Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assay				Bioorg Med Chem Lett 27: 4735-4740 (2017) Article DOI: 10.1016/j.bmcl.2017.08.068 BindingDB Entry DOI: 10.7270/Q2NG4T34
					More data for this Ligand-Target Pair