null

SMILES: Cn1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O

InChI Key: InChIKey=YWJGVHDHQUUQEH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50261863   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50261863 (CHEMBL4061455) Show SMILES Cn1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O Show InChI InChI=1S/C9H6Cl2IN3O/c1-15-7(12)6(11)5-3(10)2-4(8(13)16)14-9(5)15/h2H,1H3,(H2,13,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
IDD Medicinal Chemistry, Sanofi Genzyme, 153 Second Avenue, Waltham, MA 02451, USA. Electronic address: claude.barberis2@sanofi.com. Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assay				Bioorg Med Chem Lett 27: 4735-4740 (2017) Article DOI: 10.1016/j.bmcl.2017.08.068 BindingDB Entry DOI: 10.7270/Q2NG4T34
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50261863 (CHEMBL4061455) Show SMILES Cn1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O Show InChI InChI=1S/C9H6Cl2IN3O/c1-15-7(12)6(11)5-3(10)2-4(8(13)16)14-9(5)15/h2H,1H3,(H2,13,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
IDD Medicinal Chemistry, Sanofi Genzyme, 153 Second Avenue, Waltham, MA 02451, USA. Electronic address: claude.barberis2@sanofi.com. Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assay				Bioorg Med Chem Lett 27: 4735-4740 (2017) Article DOI: 10.1016/j.bmcl.2017.08.068 BindingDB Entry DOI: 10.7270/Q2NG4T34
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50261863 (CHEMBL4061455) Show SMILES Cn1c(I)c(Cl)c2c(Cl)cc(nc12)C(N)=O Show InChI InChI=1S/C9H6Cl2IN3O/c1-15-7(12)6(11)5-3(10)2-4(8(13)16)14-9(5)15/h2H,1H3,(H2,13,16)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
IDD Medicinal Chemistry, Sanofi Genzyme, 153 Second Avenue, Waltham, MA 02451, USA. Electronic address: claude.barberis2@sanofi.com. Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin) assessed as reduction in BAD phosphorylation at Ser112 residues by TR-FRET assay				Bioorg Med Chem Lett 27: 4735-4740 (2017) Article DOI: 10.1016/j.bmcl.2017.08.068 BindingDB Entry DOI: 10.7270/Q2NG4T34
					More data for this Ligand-Target Pair