BDBM50261976 3-(3-fluoropyridin-4-yl)-6-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)pyrazolo[1,5-a]pyrimidine::CHEMBL468003

SMILES: CN1CCN(CCOc2ccc(cc2)-c2cnc3c(cnn3c2)-c2ccncc2F)CC1

InChI Key: InChIKey=NZQQJFKFNKHJRT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261976   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261976 (3-(3-fluoropyridin-4-yl)-6-(4-(2-(4-methylpiperazi...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cnc3c(cnn3c2)-c2ccncc2F)CC1 Show InChI InChI=1S/C24H25FN6O/c1-29-8-10-30(11-9-29)12-13-32-20-4-2-18(3-5-20)19-14-27-24-22(15-28-31(24)17-19)21-6-7-26-16-23(21)25/h2-7,14-17H,8-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair