BDBM50261990 1-(3-(6-Cyanopiridin-2-yl)-1,2,4-oxadiazol-5-yl)-7-phenylheptan-1-one::CHEMBL469241

SMILES: O=C(CCCCCCc1ccccc1)c1nc(no1)-c1cccc(n1)C#N

InChI Key: InChIKey=GFIUMTOKRQIOFB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50261990 (1-(3-(6-Cyanopiridin-2-yl)-1,2,4-oxadiazol-5-yl)-7...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc(no1)-c1cccc(n1)C#N Show InChI InChI=1S/C21H20N4O2/c22-15-17-12-8-13-18(23-17)20-24-21(27-25-20)19(26)14-7-2-1-4-9-16-10-5-3-6-11-16/h3,5-6,8,10-13H,1-2,4,7,9,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibition of rat FAAH expressed in Escherichia coli				J Med Chem 51: 4392-403 (2008) Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3
					More data for this Ligand-Target Pair
Sn1-specific diacylglycerol lipase alpha (Homo sapiens (Human))	BDBM50261990 (1-(3-(6-Cyanopiridin-2-yl)-1,2,4-oxadiazol-5-yl)-7...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc(no1)-c1cccc(n1)C#N Show InChI InChI=1S/C21H20N4O2/c22-15-17-12-8-13-18(23-17)20-24-21(27-25-20)19(26)14-7-2-1-4-9-16-10-5-3-6-11-16/h3,5-6,8,10-13H,1-2,4,7,9,14H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assay				J Med Chem 58: 9742-53 (2015) Article DOI: 10.1021/acs.jmedchem.5b01627 BindingDB Entry DOI: 10.7270/Q2D50QZ9
					More data for this Ligand-Target Pair