Found 4 hits for monomerid = 50262174 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM50262174
(2-(6-(1H-pyrazol-4-yl)-2,3-dihydrobenzo[b][1,4]oxa...)Show SMILES CC1(C)Cc2nc(sc2C(=O)C1)N1CCOc2ccc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H20N4O2S/c1-20(2)8-14-18(16(25)9-20)27-19(23-14)24-5-6-26-17-4-3-12(7-15(17)24)13-10-21-22-11-13/h3-4,7,10-11H,5-6,8-9H2,1-2H3,(H,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB
Curated by ChEMBL
| Assay Description
Inhibition of PI3K delta (unknown origin) |
Bioorg Med Chem Lett 18: 4700-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.104
BindingDB Entry DOI: 10.7270/Q2VM4C2J |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM50262174
(2-(6-(1H-pyrazol-4-yl)-2,3-dihydrobenzo[b][1,4]oxa...)Show SMILES CC1(C)Cc2nc(sc2C(=O)C1)N1CCOc2ccc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H20N4O2S/c1-20(2)8-14-18(16(25)9-20)27-19(23-14)24-5-6-26-17-4-3-12(7-15(17)24)13-10-21-22-11-13/h3-4,7,10-11H,5-6,8-9H2,1-2H3,(H,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 298 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB
Curated by ChEMBL
| Assay Description
Inhibition of PI3K beta (unknown origin) |
Bioorg Med Chem Lett 18: 4700-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.104
BindingDB Entry DOI: 10.7270/Q2VM4C2J |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM50262174
(2-(6-(1H-pyrazol-4-yl)-2,3-dihydrobenzo[b][1,4]oxa...)Show SMILES CC1(C)Cc2nc(sc2C(=O)C1)N1CCOc2ccc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H20N4O2S/c1-20(2)8-14-18(16(25)9-20)27-19(23-14)24-5-6-26-17-4-3-12(7-15(17)24)13-10-21-22-11-13/h3-4,7,10-11H,5-6,8-9H2,1-2H3,(H,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 188 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB
Curated by ChEMBL
| Assay Description
Inhibition of PI3K alpha (unknown origin) |
Bioorg Med Chem Lett 18: 4700-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.104
BindingDB Entry DOI: 10.7270/Q2VM4C2J |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM50262174
(2-(6-(1H-pyrazol-4-yl)-2,3-dihydrobenzo[b][1,4]oxa...)Show SMILES CC1(C)Cc2nc(sc2C(=O)C1)N1CCOc2ccc(cc12)-c1cn[nH]c1 Show InChI InChI=1S/C20H20N4O2S/c1-20(2)8-14-18(16(25)9-20)27-19(23-14)24-5-6-26-17-4-3-12(7-15(17)24)13-10-21-22-11-13/h3-4,7,10-11H,5-6,8-9H2,1-2H3,(H,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB
Curated by ChEMBL
| Assay Description
Inhibition of PI3K gamma (unknown origin) |
Bioorg Med Chem Lett 18: 4700-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.104
BindingDB Entry DOI: 10.7270/Q2VM4C2J |
More data for this
Ligand-Target Pair | |
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