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SMILES: COC(=O)C(CCCN1CCN(Cc2ccc(F)cc2)CC1)(C(C)C)c1ccc(Br)cc1

InChI Key: InChIKey=ITWYTIMGSRUMGF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262184   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent T-type calcium channel subunit alpha-1G


(Homo sapiens (Human))		BDBM50262184
PNG
(CHEMBL466768 | methyl 5-(4-(4-fluorobenzyl)piperaz...)
Show SMILES COC(=O)C(CCCN1CCN(Cc2ccc(F)cc2)CC1)(C(C)C)c1ccc(Br)cc1
Show InChI InChI=1S/C26H34BrFN2O2/c1-20(2)26(25(31)32-3,22-7-9-23(27)10-8-22)13-4-14-29-15-17-30(18-16-29)19-21-5-11-24(28)12-6-21/h5-12,20H,4,13-19H2,1-3H3
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Article
PubMed
n/an/a 1.11E+3n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Antagonist activity at T type calcium channel alpha1G (unknown origin) expressed in HEK293 cells assessed as inhibition of peak currents by whole-cel...

Bioorg Med Chem Lett 18: 4424-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.037
BindingDB Entry DOI: 10.7270/Q2TT4QRD
More data for this
Ligand-Target Pair