BDBM50262449 CHEMBL514706::N-(4-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-2-methylbutan-2-yl)quinolin-3-amine

SMILES: CC(C)(CCc1nc(no1)-c1ccc(F)cc1Cl)Nc1cnc2ccccc2c1

InChI Key: InChIKey=PKAIHLUGFFKSDM-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50262449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50262449 (CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1...) Show SMILES CC(C)(CCc1nc(no1)-c1ccc(F)cc1Cl)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C22H20ClFN4O/c1-22(2,27-16-11-14-5-3-4-6-19(14)25-13-16)10-9-20-26-21(28-29-20)17-8-7-15(24)12-18(17)23/h3-8,11-13,27H,9-10H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in insect Sf9 cells assessed as effect on Eu-GTP binding				Bioorg Med Chem Lett 18: 4267-74 (2008) Article DOI: 10.1016/j.bmcl.2008.06.096 BindingDB Entry DOI: 10.7270/Q21C1WQ8
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50262449 (CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1...) Show SMILES CC(C)(CCc1nc(no1)-c1ccc(F)cc1Cl)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C22H20ClFN4O/c1-22(2,27-16-11-14-5-3-4-6-19(14)25-13-16)10-9-20-26-21(28-29-20)17-8-7-15(24)12-18(17)23/h3-8,11-13,27H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in insect Sf9 cells assessed as effect on Eu-GTP binding				Bioorg Med Chem Lett 18: 4267-74 (2008) Article DOI: 10.1016/j.bmcl.2008.06.096 BindingDB Entry DOI: 10.7270/Q21C1WQ8
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50262449 (CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1...) Show SMILES CC(C)(CCc1nc(no1)-c1ccc(F)cc1Cl)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C22H20ClFN4O/c1-22(2,27-16-11-14-5-3-4-6-19(14)25-13-16)10-9-20-26-21(28-29-20)17-8-7-15(24)12-18(17)23/h3-8,11-13,27H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor assessed as inhibition of forskolin-induced increase in intracellular cAMP				Bioorg Med Chem Lett 18: 4267-74 (2008) Article DOI: 10.1016/j.bmcl.2008.06.096 BindingDB Entry DOI: 10.7270/Q21C1WQ8
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50262449 (CHEMBL514706 | N-(4-(3-(2-chloro-4-fluorophenyl)-1...) Show SMILES CC(C)(CCc1nc(no1)-c1ccc(F)cc1Cl)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C22H20ClFN4O/c1-22(2,27-16-11-14-5-3-4-6-19(14)25-13-16)10-9-20-26-21(28-29-20)17-8-7-15(24)12-18(17)23/h3-8,11-13,27H,9-10H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor assessed as inhibition of forskolin-induced increase in intracellular cAMP				Bioorg Med Chem Lett 18: 4267-74 (2008) Article DOI: 10.1016/j.bmcl.2008.06.096 BindingDB Entry DOI: 10.7270/Q21C1WQ8
					More data for this Ligand-Target Pair