BDBM50262604 4-(4-methyl-1H-indol-5-ylamino)-2-(3-(pyrrolidine-1-carbonyl)phenyl)thieno[2,3-b]pyridine-5-carbonitrile::CHEMBL476746

SMILES: Cc1c(Nc2c(cnc3sc(cc23)-c2cccc(c2)C(=O)N2CCCC2)C#N)ccc2[nH]ccc12

InChI Key: InChIKey=MPKJLCGWZCOAHC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50262604 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-(pyrrolidine-...) Show SMILES Cc1c(Nc2c(cnc3sc(cc23)-c2cccc(c2)C(=O)N2CCCC2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C28H23N5OS/c1-17-21-9-10-30-24(21)8-7-23(17)32-26-20(15-29)16-31-27-22(26)14-25(35-27)18-5-4-6-19(13-18)28(34)33-11-2-3-12-33/h4-10,13-14,16,30H,2-3,11-12H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50262604 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-(pyrrolidine-...) Show SMILES Cc1c(Nc2c(cnc3sc(cc23)-c2cccc(c2)C(=O)N2CCCC2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C28H23N5OS/c1-17-21-9-10-30-24(21)8-7-23(17)32-26-20(15-29)16-31-27-22(26)14-25(35-27)18-5-4-6-19(13-18)28(34)33-11-2-3-12-33/h4-10,13-14,16,30H,2-3,11-12H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair