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SMILES: CC1CCN(CCCOc2ccc(cc2)-n2c(C)nc3ccccc3c2=O)CC1

InChI Key: InChIKey=CCCPDTOIWNMAPS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50262749   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50262749
PNG
(2-Methyl-3-(4-{[3-(4-methyl-1-piperidinyl)propyl]o...)
Show SMILES CC1CCN(CCCOc2ccc(cc2)-n2c(C)nc3ccccc3c2=O)CC1
Show InChI InChI=1S/C24H29N3O2/c1-18-12-15-26(16-13-18)14-5-17-29-21-10-8-20(9-11-21)27-19(2)25-23-7-4-3-6-22(23)24(27)28/h3-4,6-11,18H,5,12-17H2,1-2H3
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n/an/a 23n/an/an/an/an/an/a



Tsukuba Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in CHO-K1 cells

J Med Chem 51: 4780-9 (2008)


Article DOI: 10.1021/jm8003834
BindingDB Entry DOI: 10.7270/Q2FQ9WFW
More data for this
Ligand-Target Pair