BDBM50263021 Biphenyl-3,4'-dicarboxylic acid 3-cyclopropylamide 4'-cyclopropylmethyl-amide::CHEMBL479038

SMILES: O=C(NCC1CC1)c1ccc(cc1)-c1cccc(c1)C(=O)NC1CC1

InChI Key: InChIKey=GTPHSWNKNONVOX-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263021 (Biphenyl-3,4'-dicarboxylic acid 3-cyclopropylamide...) Show SMILES O=C(NCC1CC1)c1ccc(cc1)-c1cccc(c1)C(=O)NC1CC1 Show InChI InChI=1S/C21H22N2O2/c24-20(22-13-14-4-5-14)16-8-6-15(7-9-16)17-2-1-3-18(12-17)21(25)23-19-10-11-19/h1-3,6-9,12,14,19H,4-5,10-11,13H2,(H,22,24)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263021 (Biphenyl-3,4'-dicarboxylic acid 3-cyclopropylamide...) Show SMILES O=C(NCC1CC1)c1ccc(cc1)-c1cccc(c1)C(=O)NC1CC1 Show InChI InChI=1S/C21H22N2O2/c24-20(22-13-14-4-5-14)16-8-6-15(7-9-16)17-2-1-3-18(12-17)21(25)23-19-10-11-19/h1-3,6-9,12,14,19H,4-5,10-11,13H2,(H,22,24)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair