BDBM50263025 CHEMBL516287::Furan-3-carboxylic acid [4'-(cyclopropylmethyl-carbamoyl)-biphenyl-3-yl]-amide

SMILES: O=C(Nc1cccc(c1)-c1ccc(cc1)C(=O)NCC1CC1)c1ccoc1

InChI Key: InChIKey=IAMSBRBAVAWEBB-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263025 (CHEMBL516287 | Furan-3-carboxylic acid [4'-(cyclop...) Show SMILES O=C(Nc1cccc(c1)-c1ccc(cc1)C(=O)NCC1CC1)c1ccoc1 Show InChI InChI=1S/C22H20N2O3/c25-21(23-13-15-4-5-15)17-8-6-16(7-9-17)18-2-1-3-20(12-18)24-22(26)19-10-11-27-14-19/h1-3,6-12,14-15H,4-5,13H2,(H,23,25)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263025 (CHEMBL516287 | Furan-3-carboxylic acid [4'-(cyclop...) Show SMILES O=C(Nc1cccc(c1)-c1ccc(cc1)C(=O)NCC1CC1)c1ccoc1 Show InChI InChI=1S/C22H20N2O3/c25-21(23-13-15-4-5-15)17-8-6-16(7-9-17)18-2-1-3-20(12-18)24-22(26)19-10-11-27-14-19/h1-3,6-12,14-15H,4-5,13H2,(H,23,25)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair