BDBM50263066 CHEMBL478838::Furan-3-carboxylic acid [4'-(cyclopropylmethyl-carbamoyl)-6-dimethylamino-biphenyl-3-yl]-amide

SMILES: CN(C)c1ccc(NC(=O)c2ccoc2)cc1-c1ccc(cc1)C(=O)NCC1CC1

InChI Key: InChIKey=CCRHXWNYOZWLTM-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263066 (CHEMBL478838 | Furan-3-carboxylic acid [4'-(cyclop...) Show SMILES CN(C)c1ccc(NC(=O)c2ccoc2)cc1-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C24H25N3O3/c1-27(2)22-10-9-20(26-24(29)19-11-12-30-15-19)13-21(22)17-5-7-18(8-6-17)23(28)25-14-16-3-4-16/h5-13,15-16H,3-4,14H2,1-2H3,(H,25,28)(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263066 (CHEMBL478838 | Furan-3-carboxylic acid [4'-(cyclop...) Show SMILES CN(C)c1ccc(NC(=O)c2ccoc2)cc1-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C24H25N3O3/c1-27(2)22-10-9-20(26-24(29)19-11-12-30-15-19)13-21(22)17-5-7-18(8-6-17)23(28)25-14-16-3-4-16/h5-13,15-16H,3-4,14H2,1-2H3,(H,25,28)(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...				Bioorg Med Chem Lett 18: 4428-32 (2008) Article DOI: 10.1016/j.bmcl.2008.06.048 BindingDB Entry DOI: 10.7270/Q2CR5T5P
					More data for this Ligand-Target Pair