BDBM50263076 5-(3-Aminopropylamino)-7-(3,5-dimethoxyphenylamino)-1,2,4-triazolo[4,3-c]pyrimidine-8-carboxamide::CHEMBL477165

SMILES: COc1cc(Nc2nc(NCCCN)n3cnnc3c2C(N)=O)cc(OC)c1

InChI Key: InChIKey=PVAHDAYPRWZJPB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ZAP-70 (Homo sapiens (Human))	BDBM50263076 (5-(3-Aminopropylamino)-7-(3,5-dimethoxyphenylamino...) Show SMILES COc1cc(Nc2nc(NCCCN)n3cnnc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C17H22N8O3/c1-27-11-6-10(7-12(8-11)28-2)22-15-13(14(19)26)16-24-21-9-25(16)17(23-15)20-5-3-4-18/h6-9,22H,3-5,18H2,1-2H3,(H2,19,26)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of human ZAP70				Bioorg Med Chem 16: 7347-57 (2008) Article DOI: 10.1016/j.bmc.2008.06.017 BindingDB Entry DOI: 10.7270/Q2HQ3ZP6
					More data for this Ligand-Target Pair
Lysine--tRNA ligase (Homo sapiens (Human))	BDBM50263076 (5-(3-Aminopropylamino)-7-(3,5-dimethoxyphenylamino...) Show SMILES COc1cc(Nc2nc(NCCCN)n3cnnc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C17H22N8O3/c1-27-11-6-10(7-12(8-11)28-2)22-15-13(14(19)26)16-24-21-9-25(16)17(23-15)20-5-3-4-18/h6-9,22H,3-5,18H2,1-2H3,(H2,19,26)(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of human Syk				Bioorg Med Chem 16: 7347-57 (2008) Article DOI: 10.1016/j.bmc.2008.06.017 BindingDB Entry DOI: 10.7270/Q2HQ3ZP6
					More data for this Ligand-Target Pair