BDBM50263091 (R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyrrolidin-2-yl)methylamino)-2-phenylethyl 4-bromobenzoate::CHEMBL476343

SMILES: CN1[C@H](CN[C@@H](COC(=O)c2ccc(Br)cc2)c2ccccc2)[C@@H](O)[C@@H](O)C1=O

InChI Key: InChIKey=LKHOPRZQBRZOTI-WJFTUGDTSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal alpha-mannosidase (Homo sapiens (Human))	BDBM50263091 ((R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyr...) Show SMILES CN1[C@H](CN[C@@H](COC(=O)c2ccc(Br)cc2)c2ccccc2)[C@@H](O)[C@@H](O)C1=O |r| Show InChI InChI=1S/C21H23BrN2O5/c1-24-17(18(25)19(26)20(24)27)11-23-16(13-5-3-2-4-6-13)12-29-21(28)14-7-9-15(22)10-8-14/h2-10,16-19,23,25-26H,11-12H2,1H3/t16-,17+,18+,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Polytechnique Fédérale de Lausanne Curated by ChEMBL					Assay Description Inhibition of alpha-mannosidase in human LNZ308 cells				Bioorg Med Chem 16: 7337-46 (2008) Article DOI: 10.1016/j.bmc.2008.06.021 BindingDB Entry DOI: 10.7270/Q2668D0J
					More data for this Ligand-Target Pair
Lysosomal alpha-mannosidase (Homo sapiens (Human))	BDBM50263091 ((R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyr...) Show SMILES CN1[C@H](CN[C@@H](COC(=O)c2ccc(Br)cc2)c2ccccc2)[C@@H](O)[C@@H](O)C1=O |r| Show InChI InChI=1S/C21H23BrN2O5/c1-24-17(18(25)19(26)20(24)27)11-23-16(13-5-3-2-4-6-13)12-29-21(28)14-7-9-15(22)10-8-14/h2-10,16-19,23,25-26H,11-12H2,1H3/t16-,17+,18+,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Polytechnique Fédérale de Lausanne Curated by ChEMBL					Assay Description Inhibition of alpha-mannosidase in human HCEC				Bioorg Med Chem 16: 7337-46 (2008) Article DOI: 10.1016/j.bmc.2008.06.021 BindingDB Entry DOI: 10.7270/Q2668D0J
					More data for this Ligand-Target Pair
Lysosomal alpha-mannosidase (Homo sapiens (Human))	BDBM50263091 ((R)-2-(((2R,3R,4R)-3,4-dihydroxy-1-methyl-5-oxopyr...) Show SMILES CN1[C@H](CN[C@@H](COC(=O)c2ccc(Br)cc2)c2ccccc2)[C@@H](O)[C@@H](O)C1=O |r| Show InChI InChI=1S/C21H23BrN2O5/c1-24-17(18(25)19(26)20(24)27)11-23-16(13-5-3-2-4-6-13)12-29-21(28)14-7-9-15(22)10-8-14/h2-10,16-19,23,25-26H,11-12H2,1H3/t16-,17+,18+,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Polytechnique Fédérale de Lausanne Curated by ChEMBL					Assay Description Inhibition of alpha-mannosidase in human LN18 cells				Bioorg Med Chem 16: 7337-46 (2008) Article DOI: 10.1016/j.bmc.2008.06.021 BindingDB Entry DOI: 10.7270/Q2668D0J
					More data for this Ligand-Target Pair