BDBM50263127 2-Chloro-N-[4'-(cyclopropylmethyl-carbamoyl)-6-methyl-biphenyl-3-yl]-isonicotinamide::CHEMBL478225

SMILES: Cc1ccc(NC(=O)c2ccnc(Cl)c2)cc1-c1ccc(cc1)C(=O)NCC1CC1

InChI Key: InChIKey=AKNCGPVDTHDMNT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50263127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50263127 (2-Chloro-N-[4'-(cyclopropylmethyl-carbamoyl)-6-met...) Show SMILES Cc1ccc(NC(=O)c2ccnc(Cl)c2)cc1-c1ccc(cc1)C(=O)NCC1CC1 Show InChI InChI=1S/C24H22ClN3O2/c1-15-2-9-20(28-24(30)19-10-11-26-22(25)12-19)13-21(15)17-5-7-18(8-6-17)23(29)27-14-16-3-4-16/h2,5-13,16H,3-4,14H2,1H3,(H,27,29)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...				Bioorg Med Chem Lett 18: 4433-7 (2008) Article DOI: 10.1016/j.bmcl.2008.06.028 BindingDB Entry DOI: 10.7270/Q2JH3M0B
					More data for this Ligand-Target Pair