BDBM50263267 3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridin-2-yl)-N-phenylacrylamide::CHEMBL475919

SMILES: Cc1c(Nc2c(cnc3sc(\C=C\C(=O)Nc4ccccc4)cc23)C#N)ccc2[nH]ccc12

InChI Key: InChIKey=QQVBBJUQEBYOFD-JXMROGBWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263267 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)Nc4ccccc4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C26H19N5OS/c1-16-20-11-12-28-23(20)9-8-22(16)31-25-17(14-27)15-29-26-21(25)13-19(33-26)7-10-24(32)30-18-5-3-2-4-6-18/h2-13,15,28H,1H3,(H,29,31)(H,30,32)/b10-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263267 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)Nc4ccccc4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C26H19N5OS/c1-16-20-11-12-28-23(20)9-8-22(16)31-25-17(14-27)15-29-26-21(25)13-19(33-26)7-10-24(32)30-18-5-3-2-4-6-18/h2-13,15,28H,1H3,(H,29,31)(H,30,32)/b10-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair