BDBM50263336 4,4'-(ethane-1,2-diyl)dibenzene-1,3-diol::CHEMBL499124::US9682910, 4,4'-(ethane-1,2diyl)dibenzene-1,3-diol (16)

SMILES: Oc1ccc(CCc2ccc(O)cc2O)c(O)c1

InChI Key: InChIKey=WKIFTWPZTZUMRN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell surface glycoprotein MUC18 (Mouse)	BDBM50263336 (4,4'-(ethane-1,2-diyl)dibenzene-1,3-diol | CHEMBL4...) Show SMILES Oc1ccc(CCc2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C14H14O4/c15-11-5-3-9(13(17)7-11)1-2-10-4-6-12(16)8-14(10)18/h3-8,15-18H,1-2H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	25
Unigen, Inc. US Patent					Assay Description All test compounds were initially dissolved in 100% DMSO at a concentration of 400 mM. The compounds were further diluted in 100% DMSO to a concentra...				US Patent US9682910 (2017) BindingDB Entry DOI: 10.7270/Q2QZ2836
					More data for this Ligand-Target Pair
Tyrosinase (Homo sapiens (Human))	BDBM50263336 (4,4'-(ethane-1,2-diyl)dibenzene-1,3-diol | CHEMBL4...) Show SMILES Oc1ccc(CCc2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C14H14O4/c15-11-5-3-9(13(17)7-11)1-2-10-4-6-12(16)8-14(10)18/h3-8,15-18H,1-2H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Utsunomiya University Curated by ChEMBL					Assay Description Inhibition of Tyrosinase				Eur J Med Chem 46: 1374-81 (2011) Article DOI: 10.1016/j.ejmech.2011.01.065 BindingDB Entry DOI: 10.7270/Q20V8D41
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50263336 (4,4'-(ethane-1,2-diyl)dibenzene-1,3-diol | CHEMBL4...) Show SMILES Oc1ccc(CCc2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C14H14O4/c15-11-5-3-9(13(17)7-11)1-2-10-4-6-12(16)8-14(10)18/h3-8,15-18H,1-2H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Utsunomiya University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase				Bioorg Med Chem Lett 18: 5252-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.053 BindingDB Entry DOI: 10.7270/Q2VX0GBZ
					More data for this Ligand-Target Pair