BDBM50263364 4-fluoro-N-(2-oxo-2-(phenyl(3-(trifluoromethyl)phenyl)methylamino)ethyl)benzamide::CHEMBL479071

SMILES: Fc1ccc(cc1)C(=O)NCC(=O)NC(c1ccccc1)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=RFDAXGBKSBMVFF-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50263364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human))	BDBM50263364 (4-fluoro-N-(2-oxo-2-(phenyl(3-(trifluoromethyl)phe...) Show SMILES Fc1ccc(cc1)C(=O)NCC(=O)NC(c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H18F4N2O2/c24-19-11-9-16(10-12-19)22(31)28-14-20(30)29-21(15-5-2-1-3-6-15)17-7-4-8-18(13-17)23(25,26)27/h1-13,21H,14H2,(H,28,31)(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]glycine uptake at human glycine transporter 1 transfected in Flp-inTM-CHO				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50263364 (4-fluoro-N-(2-oxo-2-(phenyl(3-(trifluoromethyl)phe...) Show SMILES Fc1ccc(cc1)C(=O)NCC(=O)NC(c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H18F4N2O2/c24-19-11-9-16(10-12-19)22(31)28-14-20(30)29-21(15-5-2-1-3-6-15)17-7-4-8-18(13-17)23(25,26)27/h1-13,21H,14H2,(H,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50263364 (4-fluoro-N-(2-oxo-2-(phenyl(3-(trifluoromethyl)phe...) Show SMILES Fc1ccc(cc1)C(=O)NCC(=O)NC(c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H18F4N2O2/c24-19-11-9-16(10-12-19)22(31)28-14-20(30)29-21(15-5-2-1-3-6-15)17-7-4-8-18(13-17)23(25,26)27/h1-13,21H,14H2,(H,28,31)(H,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50263364 (4-fluoro-N-(2-oxo-2-(phenyl(3-(trifluoromethyl)phe...) Show SMILES Fc1ccc(cc1)C(=O)NCC(=O)NC(c1ccccc1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H18F4N2O2/c24-19-11-9-16(10-12-19)22(31)28-14-20(30)29-21(15-5-2-1-3-6-15)17-7-4-8-18(13-17)23(25,26)27/h1-13,21H,14H2,(H,28,31)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 18: 5533-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.005 BindingDB Entry DOI: 10.7270/Q2BR8S19
					More data for this Ligand-Target Pair