null

SMILES: Fc1ccc(cc1)-n1ncc(n1)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC1(CC1)C#N

InChI Key: InChIKey=DYBAKVKCQXSOQP-VWLOTQADSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50263642 (CHEMBL4081905) Show SMILES Fc1ccc(cc1)-n1ncc(n1)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C29H25FN6O3/c30-22-8-10-23(11-9-22)36-32-17-26(35-36)27(37)33-25(28(38)34-29(19-31)14-15-29)16-20-6-12-24(13-7-20)39-18-21-4-2-1-3-5-21/h1-13,17,25H,14-16,18H2,(H,33,37)(H,34,38)/t25-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorium für Organische Chemie , ETH Zurich , Vladimir-Prelog-Weg 3 , 8093 Zürich , Switzerland. Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate by fluorimetric method				J Med Chem 61: 3370-3388 (2018) Article DOI: 10.1021/acs.jmedchem.7b01870 BindingDB Entry DOI: 10.7270/Q2MC92GH
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50263642 (CHEMBL4081905) Show SMILES Fc1ccc(cc1)-n1ncc(n1)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C29H25FN6O3/c30-22-8-10-23(11-9-22)36-32-17-26(35-36)27(37)33-25(28(38)34-29(19-31)14-15-29)16-20-6-12-24(13-7-20)39-18-21-4-2-1-3-5-21/h1-13,17,25H,14-16,18H2,(H,33,37)(H,34,38)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorium für Organische Chemie , ETH Zurich , Vladimir-Prelog-Weg 3 , 8093 Zürich , Switzerland. Curated by ChEMBL					Assay Description Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric method				J Med Chem 61: 3370-3388 (2018) Article DOI: 10.1021/acs.jmedchem.7b01870 BindingDB Entry DOI: 10.7270/Q2MC92GH
					More data for this Ligand-Target Pair