BDBM50264021 CHEMBL491603::N-(4-(pyridin-2-yl)thiazol-2-yl)pyridin-4-amine

SMILES: N(c1nc(cs1)-c1ccccn1)c1ccncc1

InChI Key: InChIKey=KRUIVFJOWFQMLT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 3 (KCa2.3) (Homo sapiens (Human))	BDBM50264021 (CHEMBL491603 | N-(4-(pyridin-2-yl)thiazol-2-yl)pyr...) Show SMILES N(c1nc(cs1)-c1ccccn1)c1ccncc1 Show InChI InChI=1S/C13H10N4S/c1-2-6-15-11(3-1)12-9-18-13(17-12)16-10-4-7-14-8-5-10/h1-9H,(H,14,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay				Bioorg Med Chem Lett 18: 5316-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.023 BindingDB Entry DOI: 10.7270/Q2N87BP1
					More data for this Ligand-Target Pair