BDBM50264063 (2R,3S)-iodoreboxetine::(R)-2-((S)-(2-ethoxyphenoxy)(4-iodophenyl)methyl)morpholine::CHEMBL490995
SMILES: CCOc1ccccc1O[C@H]([C@H]1CNCCO1)c1ccc(I)cc1
InChI Key: InChIKey=RVASAZVCHKJYMY-MOPGFXCFSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transporter (Rattus norvegicus (rat)) | BDBM50264063 ((2R,3S)-iodoreboxetine | (R)-2-((S)-(2-ethoxypheno...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 58.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Glasgow Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysis | Bioorg Med Chem Lett 19: 4996-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.064 BindingDB Entry DOI: 10.7270/Q22V2G5N | |||||||||||
More data for this Ligand-Target Pair |