BDBM50264074 CHEMBL510166::N,4-Diphenylthiazol-2-amine

SMILES: N(c1nc(cs1)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=FAXWKQAPUYLLPC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 3 (KCa2.3) (Homo sapiens (Human))	BDBM50264074 (CHEMBL510166 | N,4-Diphenylthiazol-2-amine) Show SMILES N(c1nc(cs1)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C15H12N2S/c1-3-7-12(8-4-1)14-11-18-15(17-14)16-13-9-5-2-6-10-13/h1-11H,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay				Bioorg Med Chem Lett 18: 5316-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.023 BindingDB Entry DOI: 10.7270/Q2N87BP1
					More data for this Ligand-Target Pair
Fructose-1,6-bisphosphatase 1 (FBPase) (Sus scrofa (Pig))	BDBM50264074 (CHEMBL510166 | N,4-Diphenylthiazol-2-amine) Show SMILES N(c1nc(cs1)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C15H12N2S/c1-3-7-12(8-4-1)14-11-18-15(17-14)16-13-9-5-2-6-10-13/h1-11H,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
Boston College Curated by ChEMBL					Assay Description Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometry				Bioorg Med Chem 17: 3916-22 (2009) Article DOI: 10.1016/j.bmc.2009.04.030 BindingDB Entry DOI: 10.7270/Q25T3KGW
					More data for this Ligand-Target Pair