BDBM50264075 2-(4-(pyridin-2-yl)thiazol-2-yl)pyridine::CHEMBL523626

SMILES: c1sc(nc1-c1ccccn1)-c1ccccn1

InChI Key: InChIKey=AQRRBNTVDFDFLM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 3 (KCa2.3) (Homo sapiens (Human))	BDBM50264075 (2-(4-(pyridin-2-yl)thiazol-2-yl)pyridine | CHEMBL5...) Show SMILES c1sc(nc1-c1ccccn1)-c1ccccn1 Show InChI InChI=1S/C13H9N3S/c1-3-7-14-10(5-1)12-9-17-13(16-12)11-6-2-4-8-15-11/h1-9H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assay				Bioorg Med Chem Lett 18: 5316-9 (2008) Article DOI: 10.1016/j.bmcl.2008.08.023 BindingDB Entry DOI: 10.7270/Q2N87BP1
					More data for this Ligand-Target Pair