BDBM50264282 5-(5,5-dimethyl-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile::CHEMBL522264

SMILES: Cn1c(ccc1-c1ccc2NC(=O)COC(C)(C)c2c1)C#N

InChI Key: InChIKey=JJPAJQLMLIXBNX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50264282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50264282 (5-(5,5-dimethyl-2-oxo-1,2,3,5-tetrahydrobenzo[e][1...) Show SMILES Cn1c(ccc1-c1ccc2NC(=O)COC(C)(C)c2c1)C#N Show InChI InChI=1S/C17H17N3O2/c1-17(2)13-8-11(15-7-5-12(9-18)20(15)3)4-6-14(13)19-16(21)10-22-17/h4-8H,10H2,1-3H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Activity at progesterone receptor assessed as alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair