BDBM50264693 3-(4-(3-butyl-2-(4-fluorophenyl)naphthalen-1-yloxy)phenyl)acrylic acid::CHEMBL523138
SMILES: CCCCc1cc2ccccc2c(Oc2ccc(\C=C\C(O)=O)cc2)c1-c1ccc(F)cc1
InChI Key: InChIKey=MDBIUAHKJNWVHH-WOJGMQOQSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estradiol receptor beta (ERβ) (Homo sapiens (Human)) | BDBM50264693 (3-(4-(3-butyl-2-(4-fluorophenyl)naphthalen-1-yloxy...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from full length biotinylated human ERbeta by scintillation proximity assay | Bioorg Med Chem Lett 18: 5075-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.121 BindingDB Entry DOI: 10.7270/Q2C53KNF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50264693 (3-(4-(3-butyl-2-(4-fluorophenyl)naphthalen-1-yloxy...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 724 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Research Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from full length biotinylated human ERalpha by scintillation proximity assay | Bioorg Med Chem Lett 18: 5075-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.121 BindingDB Entry DOI: 10.7270/Q2C53KNF | |||||||||||
More data for this Ligand-Target Pair |