BDBM50265093 5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-1H-benzo[d]imidazole-2(3H)-thione::CHEMBL495723

SMILES: Fc1ccc2n(-c3ccc(OCCCN4CCCCC4)cc3)c(=S)[nH]c2c1

InChI Key: InChIKey=JUGGIWHGQWMUBH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50265093 (5-fluoro-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)-1...) Show SMILES Fc1ccc2n(-c3ccc(OCCCN4CCCCC4)cc3)c(=S)[nH]c2c1 Show InChI InChI=1S/C21H24FN3OS/c22-16-5-10-20-19(15-16)23-21(27)25(20)17-6-8-18(9-7-17)26-14-4-13-24-11-2-1-3-12-24/h5-10,15H,1-4,11-14H2,(H,23,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in HEK cells by scintillation counting				Bioorg Med Chem Lett 18: 5032-6 (2008) Article DOI: 10.1016/j.bmcl.2008.08.008 BindingDB Entry DOI: 10.7270/Q2CZ370Q
					More data for this Ligand-Target Pair