BDBM50265412 4-(2-(4-Fluorophenyl)-7-{[(2-methoxyethyl)methylamino] methyl}imidazo[1,2-a]pyridin-3-yl)pyrimidin-2-ylamine::CHEMBL497808

SMILES: COCCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1

InChI Key: InChIKey=FJVRSAQQXGOXKH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265412 (4-(2-(4-Fluorophenyl)-7-{[(2-methoxyethyl)methylam...) Show SMILES COCCN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C22H23FN6O/c1-28(11-12-30-2)14-15-8-10-29-19(13-15)27-20(16-3-5-17(23)6-4-16)21(29)18-7-9-25-22(24)26-18/h3-10,13H,11-12,14H2,1-2H3,(H2,24,25,26)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair