BDBM50265414 3-(2-Aminopyrimidin-4-yl)-2-(4-fluorophenyl)-N,Ndimethylimidazo[ 1,2-a]pyridine-7-carboxamidine::CHEMBL526655

SMILES: CN(C)C(=N)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1

InChI Key: InChIKey=OAKKCWNJPPQZPK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50265414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Eimeria tenella)	BDBM50265414 (3-(2-Aminopyrimidin-4-yl)-2-(4-fluorophenyl)-N,Ndi...) Show SMILES CN(C)C(=N)c1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(N)n1 Show InChI InChI=1S/C20H18FN7/c1-27(2)19(22)13-8-10-28-16(11-13)26-17(12-3-5-14(21)6-4-12)18(28)15-7-9-24-20(23)25-15/h3-11,22H,1-2H3,(H2,23,24,25)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
SCYNEXIS, Inc. Curated by ChEMBL					Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase				Eur J Med Chem 43: 1123-51 (2008) Article DOI: 10.1016/j.ejmech.2007.09.013 BindingDB Entry DOI: 10.7270/Q28C9W1H
					More data for this Ligand-Target Pair